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  • 21/04/19 19:55
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gregory16 자기 소개가 없습니다.

Seeking Alpha는 “미 질병통제관리센터(CDC)의 데이터에 따르면, 주 정부들이 연방정부로 부터 할당받은 Moderna(MRNA)와 Pfizer(PFE)의 코로나19 백신 공급을 소폭 늘릴 것으로 나타났다”고 보도했다.

“CDC의 이번 데이터는 CDC 패널이 백신 접종자 중 혈전이 발생한 경우를 조사함에 따라 미 연방정부가 Johnson & Johnson(JNJ)의 백신을 전혀 할당하고 있지 않고 있음을 보여주고 있다”고 전했다.

“이번주 미 각 주에는 Moderna 백신 748만 회분과 Pfizer 백신 1,010만 회분이 공급될 예정이다.지난주에는 Moderna 695.7만 회분, Pfizer 940만 회분이 지급되었다”고 전했다.

한편 16일(금) Moderna는 6.84%, Pfizer는 2.58% 상승했다.
 






FDA  CTAP Dashboard

This dashboard provides a snapshot of development of potential COVID-19 therapeutics. Given the urgent nature of the pandemic and the number of companies and researchers developing COVID-19 related therapies, the following numbers may change frequently. FDA will update these numbers monthly. As of March 31, 2021, the snapshot is:

Snapshot of development of potential COVID-19 therapeutics: 600+ Drug development programs in planning stages; 440+ Trials by FDA; 10 COVID-19 treatments currently authorized by Emergency Use; 1 Treatment currently approved by FDA for use on COVID-19
1Active Pre-INDs. Excludes vaccines.
2Safe to proceed INDs. Excludes vaccines.
3Please see the Emergency Use Authorization webpage for more details. This number includes 1 EUA authorizing both medical devices and a drug for emergency use.

Type of COVID-19 Treatment Being Studied
1 Corresponds to number of safe to proceed INDs. Excludes INDs related to vaccines
2 For additional information, please see Cellular & Gene Therapy Products
3 Includes INDs with more than one product

The categories in this bar chart span a number of categories.

Antiviral drugs keep viruses from multiplying and are used to treat many viral infections (such as HIV, Herpes, Hepatitis C, and influenza).  

Immunomodulators are aimed at tamping down the body’s own immune reaction to the virus, in cases where the body’s reaction basically goes overboard and starts attacking the patient’s own organs.

Neutralizing antibody therapies may help individuals fight the virus and include manufactured antibodies, animal-sourced antibody therapies, and blood-derived products such as convalescent plasma and hyperimmune globulin, which contain antibodies taken from people who have previously had COVID-19.

Cell therapy products include cellular immunotherapies and other types of both autologous and allogeneic cells, such as stem cells, and related products.

Gene therapy products seek to modify or manipulate the expression of a gene or to alter the biological properties of living cells for therapeutic use.

The diversity of therapeutic approaches being investigated is important because it rapidly expands our understanding of the effect of different categories of potential treatments.


Stage of COVID-19 Trials in the U.S - 100+ Early stage Trials testing safety and dosing; 330+ Late stage efficacy and safety
1 Early stage = phase 0, 1, and 1/2; Late stage = phase 2, 2/3, 3, 4.

Ongoing trials fall into two categories: early stage and late stage.

Early stage trials test safety and sometimes dosing. They rarely provide sufficient evidence to support Emergency Use Authorization or approval.

Late stage trials assess safety and establish whether the treatment is effective. They may generate sufficient evidence to support the statutory standards for Emergency Use Authorization or approval.

For additional information regarding the different phases of clinical trials, please visit: What Are the Different Types of Clinical Research?


Key Resources on Therapeutic Development  

We understand companies, researchers, patients and consumers need timely information on therapeutic development for COVID-19. Below are key resources for researchers and therapeutic developers, and patients and consumers.